TUMOR NEUROEPITELIAL POLIMORFO JUVENIL DE BAJO GRADO: REPORTE DE CASO Y REVISION DE LA LITERATURA
DOI:
https://doi.org/10.51437/nj.v25i3.87Palabras clave:
Tumores cerebrales, gliomas de bajo grado, tumor neuroepitelial polimorfo juvenil de bajo grado, inmunohistoquímica, protooncogénResumen
El tumor neuroepitelial polimorfo juvenil de bajo grado es un tumor recientemente descrito, actualmente, hay únicamente 5 reportes de caso en la literatura previos a esta publicación; este tipo de tumor es considerado como un tumor cerebral de bajo grado, el cual muestra características celulares histologías similares a los oligodendrogliomas, con marcada e intensa expresión para CD34 y ausencia de codeleción 1p/19q, además de esto, tiene un perfil de metilación y alteraciones genéticas que lo hacen diferente al resto de tumores gliales de bajo grado.
Citas
Al Barbarawi, M. M. A., Allouh, M. Z. and Qudsieh, S. M. A. (2012) ‘Neuronal and Mixed Neuronal-Glial Tumors of the Central Nervous System Chapter’, Histopathology – Reviews and Recent Advances cerebrum, 1, pp. 196–246. doi: http://dx.doi.org/10.5772/50733.
Bitar, M., Danish, S. F. and Rosenblum, M. K. (2018) ‘A newly diagnosed case of polymorphous low-grade neuroepithelial tumor of the young’, Clinical neuropathology, 37(4), pp. 178–181. doi: 10.5414/NP301081.
Dang, M. and Phillips, P. C. (2017) ‘Pediatric Brain Tumors’, Continuum, 23(6), pp. 1727–1757.
Ferris, S. P. et al. (2017) ‘Characterization of gliomas : from morphology to molecules’, Virchows Arch. Virchows Archiv. doi: 10.1007/s00428-017-2181-4.
Foster, M. T., Harishchandra, L. S. and Mallucci, C. (2018) ‘Pediatric Central Nervous System Tumors : State-of-the-Art and Debated Aspects’, Frontiers in Pediatrics, 6(November), pp. 1–8. doi: 10.3389/fped.2018.00309.
Huse, J. T. et al. (2016) ‘Polymorphous low ‑ grade neuroepithelial tumor of the young ( PLNTY ): an epileptogenic neoplasm with oligodendroglioma ‑ like components , aberrant CD34 expression , and genetic alterations involving the MAP kinase pathway’, Acta Neuropathologica. Springer Berlin Heidelberg. doi: 10.1007/s00401-016-1639-9.
Komori, T. (2017) ‘Nervous System : The Major Points of Revision’, Neurol Med Chir, 57, pp. 301–311. doi: 10.2176/nmc.ra.2017-0010.
Louis, D. N. et al. (2016) ‘The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary’, Acta Neuropathologica. Springer Berlin Heidelberg, 131(6), pp. 803–820. doi: 10.1007/s00401-016-1545-1.
Ostrom, Q. T. et al. (2018) ‘CBTRUS Statistical Report : Primary Brain and Other Central Nervous System Tumors Diagnosed in the’, Neuro-oncology, 20(S4), pp. 1–86. doi: 10.1093/neuonc/noy131.
Riva, G. et al. (2018) ‘Case Report Low-grade neuroepithelial tumor : Unusual presentation in an adult without history of seizures’, Neuropathology, 3(April), pp. 1–4. doi: 10.1111/neup.12504.
Tan, C. L. and Mclendon, R. E. (2018) ‘Histological approach to neuronal and mixed neuronal ‑ glial tumors of the central nervous system’, Glioma, 1, pp. 89–96. doi: 10.4103/glioma.glioma.
Udaka, Y. T. and Packer, R. J. (2018) ‘Pediatric Brain Tumors’, Neurologic Clinics of NA. Elsevier Inc, 36(3), pp. 533–556. doi: https://doi.org/10.1016/j.ncl.2018.04.009.
Wesseling, P. and Capper, D. (2018) ‘WHO 2016 Classification of gliomas’, Neuropathology and Applied Neurobiology, 44, pp. 139–150. doi: 10.1111/nan.12432.
Zhang, K. and Sassoon, A. (2018) ‘Polymorphous Low-Grade Neuroepithelial tumor of the Young (PLNTY): Two Cases of the Recently Described Epileptogenic Neoplasm With Oligodendroglioma-Like Components and Heavy Calcificatio’, Am J Clin Pathol, 150(1–55), pp. 16–17. doi: 10.1093/AJCP/AQY090.
Bitar, M., Danish, S. F. and Rosenblum, M. K. (2018) ‘A newly diagnosed case of polymorphous low-grade neuroepithelial tumor of the young’, Clinical neuropathology, 37(4), pp. 178–181. doi: 10.5414/NP301081.
Dang, M. and Phillips, P. C. (2017) ‘Pediatric Brain Tumors’, Continuum, 23(6), pp. 1727–1757.
Ferris, S. P. et al. (2017) ‘Characterization of gliomas : from morphology to molecules’, Virchows Arch. Virchows Archiv. doi: 10.1007/s00428-017-2181-4.
Foster, M. T., Harishchandra, L. S. and Mallucci, C. (2018) ‘Pediatric Central Nervous System Tumors : State-of-the-Art and Debated Aspects’, Frontiers in Pediatrics, 6(November), pp. 1–8. doi: 10.3389/fped.2018.00309.
Huse, J. T. et al. (2016) ‘Polymorphous low ‑ grade neuroepithelial tumor of the young ( PLNTY ): an epileptogenic neoplasm with oligodendroglioma ‑ like components , aberrant CD34 expression , and genetic alterations involving the MAP kinase pathway’, Acta Neuropathologica. Springer Berlin Heidelberg. doi: 10.1007/s00401-016-1639-9.
Komori, T. (2017) ‘Nervous System : The Major Points of Revision’, Neurol Med Chir, 57, pp. 301–311. doi: 10.2176/nmc.ra.2017-0010.
Louis, D. N. et al. (2016) ‘The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary’, Acta Neuropathologica. Springer Berlin Heidelberg, 131(6), pp. 803–820. doi: 10.1007/s00401-016-1545-1.
Ostrom, Q. T. et al. (2018) ‘CBTRUS Statistical Report : Primary Brain and Other Central Nervous System Tumors Diagnosed in the’, Neuro-oncology, 20(S4), pp. 1–86. doi: 10.1093/neuonc/noy131.
Riva, G. et al. (2018) ‘Case Report Low-grade neuroepithelial tumor : Unusual presentation in an adult without history of seizures’, Neuropathology, 3(April), pp. 1–4. doi: 10.1111/neup.12504.
Tan, C. L. and Mclendon, R. E. (2018) ‘Histological approach to neuronal and mixed neuronal ‑ glial tumors of the central nervous system’, Glioma, 1, pp. 89–96. doi: 10.4103/glioma.glioma.
Udaka, Y. T. and Packer, R. J. (2018) ‘Pediatric Brain Tumors’, Neurologic Clinics of NA. Elsevier Inc, 36(3), pp. 533–556. doi: https://doi.org/10.1016/j.ncl.2018.04.009.
Wesseling, P. and Capper, D. (2018) ‘WHO 2016 Classification of gliomas’, Neuropathology and Applied Neurobiology, 44, pp. 139–150. doi: 10.1111/nan.12432.
Zhang, K. and Sassoon, A. (2018) ‘Polymorphous Low-Grade Neuroepithelial tumor of the Young (PLNTY): Two Cases of the Recently Described Epileptogenic Neoplasm With Oligodendroglioma-Like Components and Heavy Calcificatio’, Am J Clin Pathol, 150(1–55), pp. 16–17. doi: 10.1093/AJCP/AQY090.
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Publicado
2020-03-27
Cómo citar
Gomez-Vega, J. C., Zúñiga, M. I., Meek Benigni, E., & Feo-Lee, O. H. (2020). TUMOR NEUROEPITELIAL POLIMORFO JUVENIL DE BAJO GRADO: REPORTE DE CASO Y REVISION DE LA LITERATURA. Neurociencias Journal, 25(3), 50–61. https://doi.org/10.51437/nj.v25i3.87
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